Amplification of brain self-repair processes translating into persistent functional recovery.
A 3-month course with NeuroAiD:
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Increases by 50% the odds of achieving functional independence at 6 months.1
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Enhances persistent functional recovery and independence on top of rehabilitation for up to 2 years.1,2,3
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Improves motor recovery with benefits observed as early as 1 month of treatment and at each time point up to 3 months.4
The CHIMES-E Study, functional recovery over 2 years.1
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Pre-planned study on 880 subjects* with Acute Ischaemic Stroke followed up for 2 years.
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Randomised to 3 months of either NeuroAiD or placebo.
+50% in odds of achieving functional independence at 6 months.
Persistent recovery with benefits observed over 2 years
In subjects with 2 to 4 prognostic factors of poorer outcome** and receiving NeuroAiD2 :
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More subjects achieved functional independence over time versus placebo.
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Significant improvements observed as early as 3 months.
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Less subjects deteriorating over time versus placebo, illustrating the persistence of the recovery
*CHIMES-E published in
Cerebrovascular Diseases journal is the pre-planned extended follow-up to 24 months of the CHIMES study
5, a 3-month study conducted on 1099 subjects. The CHIMES study was published in
Stroke journal in 2013.
**Prognostic factors are defined as older age, female sex, baseline NIHSS score ≥ 10 and time to first dose 48h.
Combining NeuroAiD and Rehabilitation doubles the odds of achieving functional independence versus Rehabilitation alone.3
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Analysis of 380 subjects having received rehabilitation during 3 months of NeuroAiD (n=200) or placebo (n=180).
+50% in odds of achieving functional independence at 6 months.
Persistent recovery with benefits observed over 2 years
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Statistically significant odds ratio at all time points from 3 months to 2 years from stroke onset.
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Persistent recovery with benefits sustained for up to 2 years, as supported by low Numbers Needed to Treat (NNT) range from 5 to 7 over the 24-month follow-up period.
NeuroAiD improves motor recovery.4
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Randomised double-blind study placebo-controlled study in post-acute stroke subjects with upper and lower limbs deficits, included up to one month following an ischaemic stroke (n=150).
Significantly better motor recovery observed since month 1 and sustained up to month 3.